This is a draft Program Solicitation for the Building Resilient Environments for Air and Total HEalth (BREATHE) program. The BREATHE program aims to develop diagnostic and therapeutic indoor air systems that automatically detect and react to airborne pathogens and allergens. The draft solicitation will be available for comment and feedback through April 23, 2024. Questions and comments are highly encouraged and should be directed ONLY to the ARPA-H Solutions (https://solutions.arpa-h.gov/Ask-A-Question/) by the comment and feedback due date of April 23, 2024. E-mails sent directly to the Program Manger, or any other address will be disregarded. Please note this is not an invitation for solution summaries and/or proposals. Any such responses submitted to this draft solicitation will be disregarded. ARPA-H anticipates posting a final solicitation in May 2024. See the attached draft Program Solicitation.