This is a Combined Synopsis/ Solicitation Announcement for The National Institutes of Health (NIH), National Institute on Drug Abuse (NIDA), Intramural Research Program for which the agency is seeking quotes from interested vendors to provide the requirement below. The agency requires Stereo Investigator Software for Design Based Stereology, Image Analysis, and 2D Anatomical Mapping to include six months of software support: Software requires Windows 2000 or XP Operating System. Requirement also to include the following items: Description Qty Image Stack Module for acquisition/analysis of confocal, brightfield and 1widefield fluorescence 3D image stacks. Capability to create and export brighfield and widefield fluorescence image stacks to offline workstations. Annual Software Upgrade and Support Subscription that includes 1Software upgrades and technical support. Software module for controlling automated microscope functions microscope 1 with motorized internal motorized Z focus drive and fluorescent filter turret Apotome Software Integration Module. 1 Focus Measurement Encoder or equivalent should provide accuracy to 0.1um 1 of the actual microscope stage focus position. It is essential that there be closed-loop focus operation for more accurate Z-axis measurements. 2-axis computer-controlled stepping motor system comprised of XY 1stepping stage with linear encoders (0.05 um resolution, <3um accuracy), joystick, slide holder and 3-axis controller (Z axis for encoder feedback) with interface to PC Software module for controlling motorized stage 1 Color camera. 1600H x 1200V picture elements native output at 10 1 frames per second. Multiple alternative binning modes (up to 8x8) at faster frame rates, 1.92 megapixel imaging. Wide-bandwidth light sensitivity, optimal for brightfield and epifluorescent 1applications. Should have a Firewire PC interface card to fit C-mount adaptor on the microscope Camera control software module. 1 PC Workstation. 3.0GHz processor, 4.0GB DDR2 NECC SDRAM @ 800MHz, 1 nVidia,8800GT 512MB dual VGA or DVI, dual monitor video card, 16x DVD+/-RW drive, 1.44MB; floppy drive, 2 x 500GB SATA 7200 RPM hard drive in RAID 1 configuration, integrated Gigabit NIC, serial port, enhanced multi-media keyboard, and optical mouse. Windows XP Pro Description Qty SP2 operating system Minimum 20-inch LCD flat panel monitor (WUXGA). 1920 x 1200 pixel 1native resolution. Image contrast ratio 3000:1, 6ms response time Calibration grid slide w/ ref. grid squares in dimensions of 25 & 250um 1Increments on-site installation and training 1 The North American Industry Classification System (NAICS) Code is 511210, Software Publishers. Please reference the combined synopsis/solicitation number NIHDA2009131 on all related correspondence. No collect calls will be accepted. No facsimile transmissions will be accepted. This request is not to be construed as a commitment on the part of the Government to award a contract, nor does the Government intend to pay for any information submitted as a result of this request. The Government will not reimburse respondents for any cost associated with submission of the information being requested or reimburse expenses incurred to interested parties for responses to this announcement. RESPONDENTS MUST SUBMIT INFORMATION VIA E-MAIL to Carol Lindsay at [email protected] no later than September 3, 2009, 5:00 PM Eastern Time for consideration. Please include Solicitation No. NIHDA2009131 on all submitted correspondence.

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