The Philadelphia Veterans Affairs Medical Center (PVAMC) is issuing a sources sought (VA244-15-N-0007) for a laboratory that can do specialized anatomic pathology testing needed to assist with surgical diagnosis. Testing includes immunohistochemical and flow cytometry testing. We are looking for a reference laboratory that provides a multi-disciplinary approach to evaluating specific types of cancer to help guide treatment decisions. The lab should have a comprehensive antibody library, a FISH probe library, and related molecular and cytogenetic testing. PVAMC is also looking for a lab that can do immunohistochemistry staining, EGFR mutations, T-cell gene rearrangements, chromosome analysis on blood, and bone marrow, HER2-FISH and various other stains needed to support these tests. Responses should be provided by Wed. 10/22/2014. Please note if you are all inclusive lab, what your turnaround times for testing are, include specifications, brochures. Below is a list of tests that would be required. Test Description IMMUNOHISTOCHEMISTRY MORPH (1) KAPPA/LAMBDA ISH SET-UP FEE:UNSUCCESSFUL CULTURE/CANCELLED TEST:NEOPLASTIC EBER ( EPSTEIN BARR VIRUS ) ISH - TECHNICAL COMPONENT ONLY CHROMOSOME ANALYSIS, BONE MARROW BCR/ABL RT-PCR (QUANTITATIVE ) EGFR MUTATION TUMOR ANALYSIS T-CELL GENE REARRANGEMENTS BY PCR CHROMOSOME ANALYSIS, LEUKEMIC BLOOD KRAS MUTATION ANALYSIS HER2 BY FISH HER2 (IHC) ER/PR ER/PR & HER2 (IHC) ER/PR & HER2 (FISH) JAK2 LYMPHOMA -TISSUE/FLUID PANEL (TF) PNH PANEL FLOW CYTOMETRY EACH ADDITIONAL MARKER COMPREHENSIVE SCREENING PANEL CLL PANEL PLASMA CELL PANEL INTERPHASE FISH YANALYZE 100-300 CELLS - 1 PROBE, 1 HYBRID INDIVIDUAL FISH PROBE (ONCOLOGY) INTERPHASE FISH YANALYZE 100-300 CELLS - 6 PROBES, 6 HYBRIDS INTERPRETATION AND REPORT INTERPHASE FISH YANALYZE 100-300 CELLS - 2 PROBES, 2 HYBRIDS INTERPHASE FISH YANALYZE 100-300 CELLS - 3 PROBES, 3 HYBRIDS INTERPHASE FISH YANALYZE 100-300 CELLS - 4 PROBES, 4 HYBRIDS UROVYSION ERCC1 ANALYSIS HER2 FISH AND HER2 BY IHC DNA & KI-67 BONE MARROW/ PERIPHERAL BLOOD MICROMETASTASES FRESH (SINGLE ANTIBODY) HMLH-1 / HMSH-2 / HMSH-6 / PMS2 BY IHC MICROSATELLITE INSTABILITY BY PCR (MSI) REFER TO ANTIBODY LIBRARY OF >200 IHC MARKERS IHC ( IMMUNOHISTOCHEMISTRY ) TECHNICAL COMPONENT ONLY IHC ( IMMUNOHISTOCHEMISTRY ) TECHNICAL COMPONENT ONLY IHC PROGNOSTIC/PREDICTIVE ( TS/EGFR/P27/P53) EGFR BY FISH COMPLETE BM MORPH STUDY: INCL BM ASPIRATE AND BIOPSY SPECIAL STAINS - GROUP II SPECIAL STAINS - GROUP II IMMUNOHISTOCHEMISTRY (1) IHC (2 MARKERS) IHC (3 MARKERS) IHC (4 MARKERS)

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