The Division of Microbiology and Infectious Diseases (DMID), National Institute of Allergy and Infectious Diseases (NIAID), NIH, DHHS, has a requirement for the design, development, maintenance and continual updating of several Bioinformatic Resource Centers. Multiple awards are contemplated. Each of the Bioinformatic Resource Centers will include databases for at least five (5) microorganisms. These scientific databases will provide the scientific community with research resources, which will provide access to a large amount of genomic and related data to facilitate the identification of potential targets for the development of vaccines, therapeutics and diagnostics. These databases will also enable comparative analysis of genomes to allow the identification of genetic polymorphisms that correlate with phenotypes such as pathogenicity, drug resistance, morbidity and infectivity. The databases must be accessible to the scientific community via an Internet website, serving as international resources for both genomic sequence data and related functional data. Organisms of particular interest are the NIAID Category A-C priority pathogens (http://www.niaid.nih.gov/dmid/bioterrorism/bandc_priority.htm) and those causing emerging and re-emerging diseases. It is anticipated that the period of performance for the contracts will be five (5) years each, beginning approximately on February 1, 2004. RFP-NIH-NIAID-DMID-04-34 will be available electronically on or about February 6, 2003 and may beaccessed through the Internet on the Contract Management Branch Homepage, by using the following electronic address and instructions: NIAID/CMB Home Page (via the WWW): Use http://www.niaid.nih.gov/contract to access the NIAID/CMB Home Page. Once at the NIAID CMB Home Page, click on the ?RFPs? link and then click on ?RFP NIH NIAID-DMID-04-34. It will also be posted on FedBizOpps at: http://www.fedbizopps.gov Any responsible Offeror may submit a proposal, which will be considered by the Government. This advertisement does not commit the Government to award a contract. No collect calls will be accepted. No facsimile transmissions will be accepted. Point of Contact Erin Goldstein, Contract Specialist, Phone 301-496-6423, Fax 301-480-5253, Email [email protected]; Jacqueline Holden, Senior Contracting Officer, Phone 301-496-7119, Fax 301-480-5253, Email [email protected]

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