The National Institute of Allergy and Infectious Diseases, NIH is competing the renewal of the Major Histocompatibility Complex (MHC) Tetramer Facility contract. This facility will provide synthesis and distribution of soluble MHC-peptide tetramer and related reagents to the global research community. Such reagents include mouse, non-human primate, and human MHC class I monomers and tetramers; custom-made mouse, non-human primate, and human class II tetramers; non-classical MHC TL, Qa-1, and mouse and human CD1 monomers and tetramers; CD1d and other MHC ligands; and fluorophores for tetramer detection. The major functions to be conducted under the contract are: A. Establish, operate, and maintain a Tetramer Production Facility B. Develop and maintain a distribution, tracking, and reporting system of reagents C. Create a Tetramer Facility website design and provide related maintenance D. Carry out Tetramer Technology Research and Development E. Provide Tetramer Facility Program Management Successful execution of these duties requires solid project management, which shall be integrated into the contract tasks. Duration of contract: 5 Years Anticipated award date: 12/31/2007 All responsible sources may submit a proposal which will be considered by the agency. This RFP will be available electronically on/about January 31, 2007, and may be accessed through the NIAID Office of Acquisitions (OA) Home Page at http://www.niaid.nih.gov/contract and on FedBizOpps. This notice does not commit the Government to award a contract. No collect calls will be accepted. No facsimile transmissions will be accepted. This notice does not commit the Government to award a contract.

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