The National Institute of Environmental Health Sciences (NIEHS) is soliciting proposals for resequencing of genome mouse strains. The overall objective of this requirement is to identify the DNA sequence of the nuclear genomes of 15 commonly used strains of inbred laboratory mice and which sequence determines the genetic basis of trait differences between the different inbred mouse strains. In so doing, the contractor shall develop a publicly available, easily accessible, annotated database. Specifically, the contractor shall determine the identify of each base in each position along each mouse chromosome and develop and maintain an annotated record of the sequence data obtained for each of 15 different inbred mouse strains. The contract is expected to cover a three-year performance period with two one-year options. The contract will be a cost reimbursement, level of effort type contract. It is anticipated that approximately 13,520 labor hours will be required each contract year. The anticipated release date of the request for proposal is February 2, 2004 with proposals due March 18, 2004. Interested firms should fax a request for RFP NIH-ES-04-02 to the attention of Ms. Jo Ann Lewis, Contracting Officer at (919) 541-2712 or send an e-mail request to
[email protected]. The electronic version of the FedBizOps synopsis will be available on the Internet at: http://www.niehs.nih.gov/dert/rcb/rfp.htm. An electronic copy of the RFP (without all attachments) will be posted to this site on or about February 2, 2004. This requirement in unrestricted. NAICS Code is 541710.