Regional Procurement Office (RPO) - East intends to negotiate on a sole source basis with Taconic Biosciences, Inc, 1 Discovery Dr, Ste 304, Rensselaer, NY, 12144-3448, to purchase Cyagen Turboknockout Gene Targeting Services for the Atlanta VA Medical Center. The following will be purchased: ITEM INFORMATION ITEM NUMBER DESCRIPTION OF SUPPLIES/SERVICES QUANTITY UNIT 0001 BACs purchased from CHORI Turnaround time: 1-2 weeks Shipped and handled by CHORI STOCK NUMBER: SPRCH-01006 1.00 EA 0002 Human SLC9A3-VSVG tag (2565bp) Turnaround time: 3-4 weeks STOCK NUMBER: SPRCH-01005 1.00 EA 0003 Turnaround time: 8-14 weeks Deliverable: TurboKnockout Gene Targeting Vector Report. Design and construction of TurboKnockoutr global knockin vector after client approval of Cyagen-proposed TurboKnockoutr gene targeting strategy. STOCK NUMBER: STKMU-03001 1.00 EA 0004 Turnaround time: 8-14 weeks. Deliverable: Correctly Targeted and Verified ES Cell Genotyping Report. TurboKnockout Vector will be purified, linearized, and electroporated into ES cells. ES cells are subjected to drug selection, screened by long range PCR, and verified for correct gene targeting by Southern blot. STOCK NUMBER: STKMU-03002 1.00 EA 0005 Turnaround time: 1-2 weeks. Chromosome counting is performed to ensure ES cells have the correct number of chromosomes. STOCK NUMBER: STKMU-03005 2.00 EA 0006 Turnaround time: 8-12 weeks. Deliverable: A minimum of 3 TurboKnockout heterozygous mutant mice STOCK NUMBER: STKMU-03003 1.00 EA 0007 Handling fee for 1 rodent crate. STOCK NUMBER: SPRCH-01009 1.00 EA 0008 Complete Taconic health monitoring report on animals composing the deliverable following importation and holding in a Taconic facility. Available within 6 weeks of importation from Cyagen and made available one week in advance of schedule shipment animals to the customer. Includes the cost of shipment of animals to the customer. STOCK NUMBER: SPRCH-01017 1.00 EA This notice of intent is not a request for competitive proposals. Any responsible sources who wish to identify their interest and capability to provide this equipment or equipment that is compatible must notify this Contract Specialist at [email protected], Friday, April 24, 2020 NLT 11:59AM EST. Telephone responses will not be accepted. Upon receipt of the interested parties' notification, the Contracting Officer will determine whether to conduct a competitive procurement or proceed with sole source negotiations.

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