The National Institute of Allergy and Infectious Diseases (NIAID) intend to procure from GE Healthcare Bio-Sciences Corp. the following:  One (1) SYS12904 SYSTEM, VP-Capillary DSC (Differential Scanning Calorimetry).  System to include:  Ultrasensitive VP-Capillary DSC MicroCalorimetry Cell VP-Control Unit with monitor for real-time operation and post run analysis; network compatible software pack with ORIGIN, VPViewer, Microsoft Winows XP Professional Autosampler unit with regulator, valve rotor; rmoVac temperature-controlled sample preparation and cleaning device with plumbing kit, cleaning kit, well trays, and covers, o-rings, temperature standards; manuals; installation and instruction; 16 week delivery.    

 The DSC system must be capable of:  evaluating a large amount of immunogens candidates for their suitability for immunogenicity experiments; testing the reactivity and physical stability of designed immunogens; direct measuring of thermal stability of proteins and other biomolecules in order to give insights into factors that stabilize or destabilize proteins, nucleic acids, micellar complexes, and other macromolecular systems, alone or as complexes.  The system will enable the Vaccine Research Center to predict shelf lives, develop purification strategies, and characterize and evaluate protein constructs or other biotherabeutic entities. 

This will be a firm fixed price contract in accordance with the statutory authority for this sole source requirement 41 U.S.C. 253 (c) (1) as implemented by FAR 6.302-1 only one source available, no substitutions possible, and this item contains proprietary information.  THIS ANNOUNCEMENT CONSTITUTES THE ONLY SOLICITATION; QUOTATIONS ARE NOT BEING REQUESTED, AND A WRITTEN SOLICITATION WILL NOT BE ISSUED.  The incorporated provisions and clauses are those in effect through Federal Acquisition Circular FAC 2005-76, dated July 25, 2014.  The associated North American Industry Classification System (NAICS) Code is 334516, which has a size standard of 500 employees.  All responsible sources who feel they can meet these requirements shall submit an offer that will be considered by the Agency.  A determination not to compete this requirement, based upon responses to this notice, is solely within the discretion of the Government.  Offers must be submitted no later than 5:00 P.M. Eastern Time Friday, August 22, 2014 through the U.S. Postal Service at the address of NIH/NIAID/AMOB, 10401 Fernwood Road, Room 2NE52F, MSC 4811, Bethesda, MD, 20817.   Email and fax submissions are acceptable.  Point of contact concerning this requirement is James Kish who can be reached by phone and 301-402-2282, or e-mailed to [email protected].