This solicitation notice follows a sources sought notice that was released on December 23, 2022 under notice number NIEHS2022-ToxDTT and pre-solicitation notice posted September 19, 2023.

The Division of Translational Toxicology (DTT) is an intramural division of the National Institute of Environmental Health Sciences, National Institutes of Health. DTT uses traditional and cutting- edge approaches to better understand how factors in our environment may impact human health. Such approaches include the conduct of toxicology studies on chemical, physical, and biological agents, as well as non-chemical stressors, using in vitro and in vivo models of health and disease.

The National Institute of Environmental Health Sciences (NIEHS) intends to negotiate and award a contract to support and assist the National Institute of Environmental Health Sciences and the and the Division of Translational Toxicology (DTT) by conducting ongoing and recurring evaluations of the toxic and carcinogenic potential of chemical, biological and physical agents that may pose a health hazard to humans. Services and support related to toxicology testing include, but are not limited to, the following: 1) customized, fit-for-purpose study designs (2) refinement of requirements after study initiation and (3) specific data collection requirements. The Contractor will conduct in vitro studies and short-term and long-term in vivo studies on a diverse array of agents by various routes of exposure.