Requirement:
The National Institutes of Health (NIH), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), is conducting a market survey to determine the availability and technical capability of qualified small business, veteran-owned small business, service-disabled veteran-owned small business or HUBZone small businesses capable of providing DEUTERIUM OXIDE (U-13C6, 99%).

Research in the Section of Protein NMR and the Protein Biophysical NMR Spectroscopy Section heavily relies on the use of isotopically enriched bacterially expressed proteins. To produce isotopically labelled protein, the e. coli cells need to be cultured in media containing isotopically enriched nutrients, i.e. 15N-labeled ammonium chloride, L-glucose of differently labeled, uniformly 13C-labeled, 13C labeled and deuterated, and deuterated). Because the large size of the proteins being studied in the lab, proteins need to be perdeuterated, and thus the e. coli needs to be cultured in the media of deuterium water.

All Capability Statements sent in response to this SOURCES SOUGHT NOTICE are due no later than 11:00 AM (EST), May 20, 2019. Responses and/or submissions via Facsimile will not be accepted. All questions pertaining to this notice must include the Notice Number specified above.

CAPABILITY STATEMENTS RECEIVED AFTER SPECIFIED DATE AND TIME WILL NOT BE CONSIDERED.

PLEASE NOTE: In order to receive an award, Contractor must be registered and have a valid certification in the System for Award Management (SAM), formerly known as Central Contractor Registration (CCR).

DISCLAIMER AND IMPORTANT NOTES: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in this response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a pre-solicitation synopsis and solicitation may be published in Federal Business Opportunities at www.fbo.gov. However, responses to this notice will not be considered adequate responses to a solicitation.

CONFIDENTIALITY: No proprietary, classified, confidential, or sensitive information
should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s).