Researchers at the National Institute of Standards and Technology (NIST) are working on the following technologies. For further information, contact the: National Institute of Standards and Technology, Office of Technology Partnerships, 100 Bureau Drive, Stop 2200, Gaithersburg, Maryland 20899; Fax: 301-975-3482. *** This is not an announcement of a contract action or a grant.*** NIST DOCKET NUMBER: 06-011 Title: Gradient Elution Moving Boundary Electrophoresis Description: Gradient Elution Moving Boundary Electrophoresis (GEMBE) is a method for performing electrophoretic separation and/or purification of compounds in a mixture. The essence of the invention is the use of a variable bulk flow in electrophoresis. The method uses the electrophoretic migration of chemical species in solution in combination with variable hydrodynamic bulk flow of the solution through a separation capilary or microfluidic channeL. GEMBE can be used with the bulk flow solution flow in either direction with respect to the electrophoretic driving force. Continuous sample introduction eliminates the need for a sample injection mechanism, allowing for significant miniaturization.

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