The chief goal of the contract is to facilitate development of a project on activity and mood disorders at the NIMH IRP at the Genetic Epidemiology Research Unit (Dr. Kathleen Merikangas, P.I.). The first phase involves development of methods for joint analysis of electronic diary and activity data, and the association between mood disorders and activity and mood regulation. The second phase involves joint analyses of NIMH data with those from other sites including Sydney, Australia (Professor Ian Hickie), Norway. The third phase involves establishment of these measures at new sites including Chengdu, China through a joint award of the National Chinese Research Council with the NIH Intramural Research Program, the CoLaus Project in Lausanne, Switzerland (Dr. Martin Preisig, PI).