RECOVERY. This notice is provided for informational purposes only. This opportunity is available only to contractors under the GSA Federal Supply Schedule 66 - Scientific Equipment and Services. The project will be funded through the American Recovery and Reinvestment Act 2009. Description of requirement: The Food and Drug Administration is soliciting for a Multi-Detection Microplate Reader with Luminescence, Fluorescence Intensity Top/Bottom, UV-Visible Absorbance and Dual Reagent Dispenser. Temperature control to 50°C and shaking are standard. Includes: • Data Analysis Software • Installation Qualification and Initial Training o Unpacking and Setup of the instrument o Initial training on the use of the instrument and/or basic overview software Specifications: • Fluorescence, Time Resolved Fluorescence, Fluorescence Polarization, Alpha Screen/ AlphaLisa, Luminescence, UV-Visible Absorbance Detection Method • End-point, kinetic, spectral scanning, well-area scanning read method • 6- to 1536-well plates (luminescence 1-384) PCR Microplate Plates Compatible with Multi-Volume Plate with 2 µL microspots • 4°C above ambient to 65°C Temperature Control • Shaking • Software Included, Control through USB or serial port • Absorbance o SQ Xenon Flash Light Source o Monochromator Wavelength Selection o 200 - 999 nm, 1 nm increment Wavelength Range o 2.4 nm Bandpass o 0 - 4.0 OD Dynamic range o 0.0001 OD Resolution o Pathlength Correction o +/- 2 nm Monochromator Wavelength Accuracy o +/- 0.2 nm Monochromator Wavelength Repeatability o < 1% at 2 OD typical accuracy < 3% at 3.0 OD typical accuracy o < 1% from 0 to 3.0 OD typical linearity o < 0.5% at 2.0 OD typical repeatability o 0.03% at 230 nm typical Stray light o 96: 11 seconds Reading speed 384: 22 seconds Reading speed 1536: 42 seconds Reading speed • Fluorescence Intensity o Fluorescein 1 pM typical (0.2 fmol/well 96-well plate; 0.1 fmol/well 384-well plate) - Top Sensitivity o Fluorescein 5 pM typical (1 fmol/well 96-well plate; 0.5 fmol/well 384-well plate) - Bottom Sensitivity o Tungsten Halogen High Energy DPR Xenon Light source Flash (optional) o Deep blocking bandpass filters/dichroic mirrors Wavelength selection o 300 - 700 nm with tungsten lamp (900 nm option) Wavelength range 200 - 700 nm with xenon lamp (900 nm option) Wavelength range o > 6 decades Dynamic range o Filter dependent Bandpass o PMT Detection system o 96: 11 seconds Reading speed 384: 22 seconds Reading speed 1536: 42 seconds Reading speed • Luminescence o 10 amol ATP typical (flash) Sensitivity o 300 - 700 nm Wavelength range o > 6 decades Dynamic range o Low noise PMT Detection system • Fluorescence Polarization o Tungsten Halogen High Energy DPR Xenon Light source Flash (optional) o 3 mP at 1 nM fluorescein typical Sensitivity o Deep blocking filters/mirrors Wavelength selection o 400 - 700 nm Wavelength range • Time-Resolved Fluorescence o High Energy DPR Xenon Flash Light source o Europium 60 fM typical (12 amol/well 96-well plate; 6 amol/well 384-well plate) Sensitivity o Deep blocking filters/mirrors Wavelength selection o 200 - 700 nM (900 nm option) Wavelength range • Reagent Dispensers o 2 syringe pumps o 5 - 1000 µL in 1 µL increment Dispense volume o 1.1 mL, 100 µL with backflush Dead volume • 250 Watts max. Power • For in vitro diagnostic use, all microplate instrumentation are to be CE and ETL marked This procurement will be firm-fixed price and will be competed under pre-existing Multiple Award Federal Supply Schedule contracts. A competitive Request for Quote (RFQ) will be issued via GSA e-Buy For information regarding this notice, please contact Howard Nesmith at (870) 543-7459, FAX (870) 543-7990 or email [email protected].

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