Federal Bid

Last Updated on 09 Mar 2021 at 7 PM
Special Notice
Location Unknown

Neurology 4-Plex Advantage Kits with SR-X Disc Kits and Wash Buffers

Solicitation ID HHSNQUANTERIX030821
Posted Date 09 Mar 2021 at 7 PM
Archive Date 09 Apr 2021 at 4 AM
NAICS Category
Product Service Code
Set Aside Total Small Business (SBA) Set-Aside (FAR 19.5)
Contracting Office Not Specified
Agency Department Of Health And Human Services
Location United states
Point Of Contact Not Available

DESCRIPTION:

The National Institutes of Health - NICHD intends to procure the services of a contractor to provide CLN3 Biomarker discovery panel: Neurology 4-Plex Advantage Kits with SR-X Disc Kits and Wash Buffers.

Project Background:

    1. Section on Molecular Dysmorpholgy investigates molecular, biochemical, cellular, and
    1. processes that underlie genetic syndromes. Specifically, the research has

focused on two rare genetic disorders, Smith-Lemli-Opitz syndrome, and Niemann-Pick

Disease, type C1. Smith-Lemli-Opitz syndrome (SLOS) is an inborn error of cholesterol

synthesis that results in birth defects and cognitive impairment. Niemann-Pick Disease, type

C1 (NPC1) is a neurodegenerative, lysosomal storage disease due to impaired intracellular

cholesterol transport. The goal of this section research efforts is to combine both basic

science and clinical expertise to develop and test novel therapeutic interventions for SLOS

and NPC1. This project seeks to identify biomarkers that may be a clinical significance.

  1. Section on Molecular Dysmorpholgy has previously demonstrated the role of Calbindin D and NFFL in Niemann-Pick Disease, type C1 (NPC1) neuroinflammation specifically within the Purkinje neurons critical from the ataxia noted as a hall mark of this disease. The plan is to further extend that research by analyzing GFAP, NF-L, Tau, and UCH-L1in the CSF of NPC pateins.

According to the Research Lab, only one”This company has the proprietary chemistry for these kits. These kits will allow the laboratory to use less sample than conventional ELISA or western blot technologies. As these are volume limited samples the less we need to use the better.”

This proposed procurement is for a service for which the government intends to solicit and negotiate on a sole source basis to Quanterix Inc.  located in 900 Middlesex Turnpike, Billerica, MA 01821.  In order to comply with the requirements in this Special Notice # HHSNQaunterix030821, the responses should be based on our interpretation of the general requirements provided below.


The proposed contract action is for a continuation of previous services for which the Government intends to solicit and negotiate with only one source under the authority of FAR 6.302. Interested persons may identify their interest and capability to respond to the requirement or submit quotations. This notice of intent is not a request for competitive quotes. However, all quotes received within the time and date of publication of this "Special Notice " will be considered by the Government for the current or future orders. A determination by the Government not to compete with this proposed contract based upon responses to this notice is solely within the discretion of the Government. Information received will normally be considered solely for the purpose of determining whether to conduct a competitive procurement.

HOW TO RESPOND: In order to compete for this project, interested parties must be registered in the Central Contracting Registration and submit a price quotation by 2:00 pm, ET, March 22th 2021. Offerors may either submit one copy of the quote to MOE FILALI by mail or preferably via email. Electronic transmissions to [email protected] are preferable but must be timely. It is the responsibility of the Offeror to ensure the proposal is received by the date and time shown above.

The following Federal Acquisition Regulations clauses are incorporated by reference: FAR 52.212-3, Offeror Representations and Certifications-Commercial Items (Mar 2005), 52.212-4 (Sept 2005), 52.212-5, Contract Terms and Conditions Required to Implement Statutes of Executive Orders-Commercial Items (Aug 2006). (6)(i) 52.222-26, Equal Opportunity (Apr 2002) (E.O. 11246). (18) 52.222-35, Equal Opportunity for Special Disabled Veterans, Veterans of the Vietnam Era, and Other Eligible Veterans (Dec 2001) (38 U.S.C. 4212). (19) 52.222-36, Affirmative Action for Workers with Disabilities (Jun 1998) (29 U.S.C. 793). (20) 52.222-37, Employment Reports on Special Disabled Veterans, Veterans of the Vietnam Era, and Other Eligible Veterans (Dec 2001) (38 U.S.C. 4212). (31) 52.232-33, Payment by Electronic Funds Transfer-Central Contractor Registration (Oct 2003) (31 U.S.C. 3332).

Primary Point of Contact:

MOE FILALI Contracting Office Address:
 

NIH/NICHD Office of Acquisitions

6710B Rockledge Drive, Room 1145D

Bethesda, MD 20817

(w) 301.827 7737

[email protected]


 

Bid Protests Not Available

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