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This is a notice of intent to increase the ceiling of Contract N66001-14-C-4016 to Wake Forest University Health Sciences, awarded by SSC Pacific on behalf of the Defense Advanced Research Projects Agency Defense Sciences Office (DARPA/DSO) on 31 January 2014 for a performance period of six (6) months. This effort extrapolated the achievements of the REMIND program to circumstances that facilitated application of the memory prosthesis device developed for nonhuman primates (NHPs), to human patients undergoing surgery for brain disease conditions such as epilepsy in order to restore retention of item specific information necessary for cognitive function. The Wake Forest team has demonstrated for the first time that a direct neural interface could be used to write in specific neural codes into the brain to facilitate memory formation and recall in human subjects. This groundbreaking discovery is advancing DARPAs neurotechnology portfolio in support of President Obamas BRAIN Initiative. This additional effort seeks to add tasking to this effort with these specific aims: 1) extend their findings to additional human patients in order to validate these results, 2) test the specificity of memory facilitation using neural stimulation codes that correspond to specific object categories and features, and 3) test the generalizability and transferability of these memory codes across humans. The NAICS code for this procurement is 541712. Due to the nature of Research and Development efforts, DARPA could not have reasonably estimated the results of the research from this program, which has seen breakthroughs that will benefit from continued research under this current contract. This action includes a ceiling increase of approximately $4,900,000. This notice of intent is not a request for competitive proposals or quotes and will be posted for 15 days. A determination by the Government not to compete based upon response to this notice is solely within the discretion of the Government. Interested parties may submit comments in writing to the Contract Specialist, Ms. Megan Ashley, Code 22530, SPAWAR Systems Center Pacific who may be reached by telephone at (619) 553-2244 or via email to [email protected].

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