The Center for Disease Control and Prevention (CDC), National Center for Environmental Health (NCEH), Division of Laboratory Science (DLS), intends to award a sole source purchase order to Promega Corporation, 2800 Woods Hollow Rd, Madison, WI 53711-5399, for the purchase of 600 vials of Trypsin Gold, Mass Spectrometry Grade, packed in 100 ug vials.

The statutory authority for this sole source acquisition is 10 U.S.C 2304(c)(1) in accordance with FAR Part 6.302-1- only one responsible source and no other supplies or services will satisfy the agency requirement. The NAICS code for this procurement is 334516, Analytical Laboratory Instrument Manufacturing.

The purpose of this acquisition is to purchase 600 vials of Trypsin Gold, Mass Spectrometry Grade, packed in 100 ug vials. Promega Corporation is the only responsible source capable of meeting the Government's requirement because they are the only vendor that can manufacture this product, meeting the required specifications (purity and size of vials). Continuity of this product's brand is vital to the continuity of the project activities. If CDC changes brands of Trypsin the existing analytical methods will require a complete evaluation of the product and a reevaluation of existing method which would cause delays in the continuity of the project.

Trypsin Gold, Mass Spectrometry Grade Enzyme is treated with TPCK to avoid self digestion of the enzyme. This enzyme is purified by affinity chromatography for best quality and specificity and it is provided as a powder for stability and storage purposes in vials of 100 micrograms. The product, which is currently in use, has been of consistent quality, efficiency and reliability to the point that it became part of CDC's Standard Operating Procedures for protein digestion.

Promega is the only manufacturer that provides the Trypsin Gold Mass Spectrometry grade in vials of 100 microgram, specifically designed for assay needs for the CDC and meets all program requirements. Thus, it is the only company that can be used.

As a result of this synopsis, no competitive solicitation will be posted on FedBizOpps. We will issue only one solicitation to Cambridge Isotope Laboratories. However, firms that believe they can meet these requirements are encouraged to identify themselves and give written notice by providing a capability statement to the Contracting Officer by May 11, 2012. The Contracting Officer will not respond to verbal request. All requests must be in writing.

A determination by the Government not to compete this proposed action will be based on responses to this notice and are solely within the discretion of the Contracting Officer. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. Inquiries shall be sent to Vallerie Redd by email at [email protected] and reference solicitation number 2012-Q-14526 on the subject line.