The purpose of this amendment is to extend the closing date to 9/6/2016, 4PM, EST.

The FDA Library routinely receives requests for an evidence based point of care decision resource tool to ensure the safety of the products FDA regulates. Medical Officer's (MO's) review an unlimited amount of data to answer safety concerns. When an adverse event is received, MO's need access to knowledge provided by expert medical specialists featuring depth and breadth of content that is peer reviewed.
Typically, MO's need to obtain background rates of disease in multiple populations, risk factors for disease occurrence, and classification schemes for syndromes, diagnostic options, and latest treatments. This information forms the basis for the foundation of the interpretation of adverse events, and it is constantly changing as the volume of medical information increases exponentially.
UpToDate, an online resource, brings all this information together in a rapidly accessible and integrated format. The subscription allows MO's to log on to UpToDate 24/7 to look up and verify information. Mobile app access is also available. The subscription service uses topic reviews that are referenced back to the original journal articles, which are written by physicians renowned in their specialty and peer reviewed by other physicians. The service is designed to assist medical professionals in their day-to-day practices.

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